Enhanced Slab Selective Brain Imaging at 3T using Wide Band Tailored RF pulses

نویسندگان

  • S. J. Malik
  • J. V. Hajnal
چکیده

Introduction T1 weighted brain imaging at 3T for both clinical and neuroscience applications is often done using slab selective MPRAGE [1] sequences that provide flexible 3D coverage. RF field (B1) non-uniformity is an inherent problem for high field MRI and for this type of sequence results in variable image contrast. In order to compensate for this, various B1 inhomogeneity mitigating RF pulses have been proposed, and for slice or slab selective imaging the most popular are the so-called "spokes" or “fast kz” [2,3] pulses. These consist of a train of slice/slab selective pulses (“spokes”) which are individually modulated to produce the desired excitation. Parallel transmission (PTx) can be incorporated into this framework, by applying different pulses on each RF coil. We designed and tested an enhanced PTx-spokes implementation of a clinically used slab selective MPRAGE protocol for at 3T.and have explored the relative merits of simple RF shimming, single channel spokes operation and full PTx with spokes.

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تاریخ انتشار 2009